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A mule is fitted for commerce with the female after the first shedding of its teeth, and at the age of seven will impregnate effectually; and where connexion has taken place with a mare, a 'hinny' has been known to be produced. After the seventh year it has no further intercourse with the female. A female mule has been known to be impregnated, but without the impregnation being followed up by parturition. In Syrophoenicia she-mules submit to the mule and bear young; but the breed, though it resembles the ordinary one, is different and specific. The hinny or stunted mule is foaled by a mare when she has gone sick during gestation, and corresponds to the dwarf in the human species and to the after-pig or scut in swine; and as is the case with dwarfs, the sexual organ of the hinny is abnormally large.

The mule lives for a number of years. There are on record cases of mules living to the age of eighty, as did one in Athens at the time of the building of the temple; this mule on account of its age was let go free, but continued to assist in dragging burdens, and would go side by side with the other draught-beasts and stimulate them to their work; and in consequence a public decree was passed forbidding any baker driving the creature away from his bread-tray. The she-mule grows old more slowly than the mule. Some assert that the she-mule menstruates by the act of voiding her urine, and that the mule owes the prematurity of his decay to his habit of smelling at the urine. So much for the modes of generation in connexion with these animals.